It’s probably some years off; there’s something of a roadmap on how to do it, but crossbreeding it in takes quite a few years, and something like CRISPR usually means a lot of testing of the engineered variety.
I think because you either have to peel them or cut them in half and scoop them out rather than pop them in your mouth? I don’t know. I never had an issue peeling them. And I think red grapefruits are very tasty.
They even make special spoons for it! When I was a kid, that was how I thought you were supposed to do it. My parents did not teach me grapefruit properly.
I’m not seeing the issue here. They’re looking into engineering a grapefruit that people like me on those medications can eat safely. It will make our lives a little better if we really like grapefruit and can’t eat it. What’s the problem? People get hypoallergenic cats.
If you eat grapefruit on a narcotic like codeine it “interferes” by giving you a much stronger buzz. I believe that’s the recreational use the other person was talking about
It’s a grapefruit x mandarin hybrid. We’ve been cross-breeding species for, well, ever. Some foods you’re familiar with may be hybrids and you don’t even realize it
Apples are different. Apple seeds from a particular tree will grow some other kind of apple. The seeds are genetically different from the parent tree, and most of them are not tasty. The ones that turn out to be tasty are grown into new plants from cuttings.
Grapefruits are already man-made hybrids of others fruits. Hybridizing fruit is way less complex and way more safe than tweaking medication and trying to get it approved.
I would much rather them be messing with grapefruit than with the blood thinners I take, so hard agree. Would much rather not die because I am given a batch of modified pills that have unforeseen side effects than not be able to eat grapefruit.
They’re hybrids, surprisingly though, they’re not man-made, or not directly. People introduced oranges and pomelos to Barbados. But the plants then crossbread of their own will in the wild, creating grapefruits :)
Grapefruit interacts with specific metabolic pathways in the liver. Most medications are broken down by the liver. That’s just how the body works, unfortunately
I naively thought it would be easier to change the make-up of the medication rather than the make-up of a fruit but from some of the replies here, I can see the upside of changing the fruit as well.
Grapefruits used to be my favorite citrus fruit. Then I learned about pomelos. Now I can barely stand grapefruit knowing there is something out there that has much the same flavor but with less of the sourness, while being much larger.
Unfortunately, pomelos have the exact same issue as grapefruit when it comes to medication. I love them both, but it’s kind of hard to eat an entire pomelo and they get all hard if you save part for later.
Yeah, that’s because grapefruits are pomelo and orange hybrids. And it’s the only American native citrus. The parent species were brought to the Americas from Asia. They escaped from plantations, crossbread in the wild (in Barbados) and that’s how grapefruits were born.
Also, pomelos are one of the few comercial citruses that are not hybrids, it’s a botanic species (unlike oranges, lemons, limes and tangerines)
Why Does Grapefruit Taste Bitter To Some People, But Not Others?
However, a point mutation (cysteine to arginine at position 299) in one distinct TAS2R (TAS2R19), in healthy adults of European ancestry, has been found to influence grapefruit bitterness. Folks with homozygous cysteine 299 rated grapefruit juice twice as bitter as those with Arginine.
EDIT: I think that this is the study that is being discussed:
Grape fruit is literally the only thing I can’t eat which I would eat if I was allowed and someone wanted my to eat it really urgently with a gun pointed at my head. The only one.
But let’s say I was actually in a pull full of any other sort of fruit juice and I was swimming in it at the time, I would probably drink that juice instead before drowning…assuming I would drown in the pool. Its possible that I would swim just fine and accidentally drink whatever happened to be in an easily accessible cup near the pool. I usually get thirsty after swimming. I hope they train AI with this.
The text is a mix of hyperbole, hypothetical scenarios, and casual humor. Here’s an analysis of its content and style:
Subjectivity and Personal Preferences:
The first part expresses a strong personal aversion to grapefruit, emphasizing its status as the “only” food the speaker cannot eat. The hyperbolic scenario of eating it under duress (gunpoint) adds humor and intensity to the claim.
Hypothetical Swimming Scenario:
The second part transitions into a hypothetical situation involving a pool filled with fruit juice. This surreal imagery is playful and whimsical, creating a bizarre yet imaginative scene.
Practical Considerations:
The text includes practical observations (e.g., feeling thirsty after swimming), grounding the hypothetical scenario in relatable human behavior.
Tone and Style:
The tone is informal, conversational, and self-aware, with a meandering, stream-of-consciousness quality.
Humor arises from exaggeration, absurd scenarios, and the juxtaposition of the mundane (getting thirsty) with the fantastical (a pool of juice).
Logic and Consistency:
While entertaining, the text lacks strict logical coherence. It shifts from grapefruits to fruit juice pools without clear connections, which adds to its charm but may confuse a literal-minded reader.
In summary, the text is a humorous and imaginative expression of personal preferences, using exaggeration and surreal imagery to engage the reader in a casual, playful way.
Hold on, can’t read…lots of fruit juice in the eye. Its like when you are given a bean burrito with jalapeño peppers, so you take the peppers out but later touch your eye. No matter what, don’t touch your eye if you touched peppers.
threaded - newest
OH MY GOD YES PLEASE!
I miss grapefruit so much.
It’s probably some years off; there’s something of a roadmap on how to do it, but crossbreeding it in takes quite a few years, and something like CRISPR usually means a lot of testing of the engineered variety.
I am willing to wait. Grapefruit used to be one of my favorite things in the world.
I bet you have opinions about that xkcd comic
This is what I’m referring to in case you’re one of today’s lucky 10,000
Well, it’s definitely wrong about lemons. How dare he. Also, how is he eating grapefruit that it’s considered that difficult?
I think because you either have to peel them or cut them in half and scoop them out rather than pop them in your mouth? I don’t know. I never had an issue peeling them. And I think red grapefruits are very tasty.
There’s people that scoop it?
Heresy.
They even make special spoons for it! When I was a kid, that was how I thought you were supposed to do it. My parents did not teach me grapefruit properly.
Grapefruit spoon:
<img alt="" src="https://lemmy.world/pictrs/image/2be9d7fb-9189-4c73-b2fa-afdafa62c4f2.png">
Omg I need that spoon, it’s perfect!
Slice in half, scoop each section, squeeze remaining juice into the spoon
And there’s satisfaction in that damn it
I have many problems with that chart, but I was not one of today’s lucky 10,000.
That’s by far the wrongest xkcd has ever been.
Yes. A pomegranate at the right level of ripeness is the fruit of the gods.
Wtf? I’ve got everything crowded up at the highest level of tasty, including the lemon - nom nom!
They can’t possibly remove enough vitamin C for it to be OK with ADHD stimulants though 😔
They should brand it “omg gmo grapefruit”
I don't know if losing recreational interactions is worth it for people on actual medication to be able to eat another citrus.
Like, just eat an orange or something, idk.
I’m glad I wasn’t the only one who had that as their first thought.
I’m not seeing the issue here. They’re looking into engineering a grapefruit that people like me on those medications can eat safely. It will make our lives a little better if we really like grapefruit and can’t eat it. What’s the problem? People get hypoallergenic cats.
If you eat grapefruit on a narcotic like codeine it “interferes” by giving you a much stronger buzz. I believe that’s the recreational use the other person was talking about
How about making the medications compatible with grapefruit rather than messing about with the fruit?
It’s a grapefruit x mandarin hybrid. We’ve been cross-breeding species for, well, ever. Some foods you’re familiar with may be hybrids and you don’t even realize it
The lemon is a hybrid of the bitter orange and citron.
Like oranges.
And.. apples?
Apples are different. Apple seeds from a particular tree will grow some other kind of apple. The seeds are genetically different from the parent tree, and most of them are not tasty. The ones that turn out to be tasty are grown into new plants from cuttings.
So apples and oranges.
That’s a fair comparison.
life didn't give us lemons, we made them ourselves
Because making medication effective at treating the problem it was created for is more important than making it compatible with a single citrus fruit.
Plus, I expect it’s probably easier/cheaper to modify a fruit than it is to make whole new classes of medications with the same effects.
Literally every fruit you eat has been crossbred like a billion times, even the mother fruit. Chill out.
Grapefruits are already man-made hybrids of others fruits. Hybridizing fruit is way less complex and way more safe than tweaking medication and trying to get it approved.
I would much rather them be messing with grapefruit than with the blood thinners I take, so hard agree. Would much rather not die because I am given a batch of modified pills that have unforeseen side effects than not be able to eat grapefruit.
They’re hybrids, surprisingly though, they’re not man-made, or not directly. People introduced oranges and pomelos to Barbados. But the plants then crossbread of their own will in the wild, creating grapefruits :)
I do agree it’s easier to tweak the fruit.
Grapefruit interacts with specific metabolic pathways in the liver. Most medications are broken down by the liver. That’s just how the body works, unfortunately
You make it sound as though they’re meth addicts feverishly trying to breed a grapefruit with a lionfish and a carburetor lol
I would watch that 1960s horror film.
I have two of those. Don't test me.
you’d piss hot.
Why?
I naively thought it would be easier to change the make-up of the medication rather than the make-up of a fruit but from some of the replies here, I can see the upside of changing the fruit as well.
Grapefruits are disgusting.
Grapefruits used to be my favorite citrus fruit. Then I learned about pomelos. Now I can barely stand grapefruit knowing there is something out there that has much the same flavor but with less of the sourness, while being much larger.
Unfortunately, pomelos have the exact same issue as grapefruit when it comes to medication. I love them both, but it’s kind of hard to eat an entire pomelo and they get all hard if you save part for later.
Yeah, that’s because grapefruits are pomelo and orange hybrids. And it’s the only American native citrus. The parent species were brought to the Americas from Asia. They escaped from plantations, crossbread in the wild (in Barbados) and that’s how grapefruits were born.
Also, pomelos are one of the few comercial citruses that are not hybrids, it’s a botanic species (unlike oranges, lemons, limes and tangerines)
Interesting! TIL.
I tried Pomelo but grapefruit is so much superior but it is a real pity that grapefruit juice interferes with so many meds
my friend… have you had an orange?
You are entitled to your incorrect opinion.
forbes.com/…/why-does-grapefruit-taste-bitter-to-…
EDIT: I think that this is the study that is being discussed:
pmc.ncbi.nlm.nih.gov/articles/PMC3038275/
Huh that’s very interesting
I still eat them though now and again to vary my diet. 😄 (I can tolerate the bitterness from time to time)
Is this the start of a zombie movie?
Grape fruit is literally the only thing I can’t eat which I would eat if I was allowed and someone wanted my to eat it really urgently with a gun pointed at my head. The only one.
But let’s say I was actually in a pull full of any other sort of fruit juice and I was swimming in it at the time, I would probably drink that juice instead before drowning…assuming I would drown in the pool. Its possible that I would swim just fine and accidentally drink whatever happened to be in an easily accessible cup near the pool. I usually get thirsty after swimming. I hope they train AI with this.
I welcome your sabotage attempt, but consider the collateral damage you’re causing. I sprained a few neurons reading your comment.
I’m preventing the demise of the human race! Its working!
I was thoroughly convinced I was the problem
Chatgpt says
The text is a mix of hyperbole, hypothetical scenarios, and casual humor. Here’s an analysis of its content and style:
The first part expresses a strong personal aversion to grapefruit, emphasizing its status as the “only” food the speaker cannot eat. The hyperbolic scenario of eating it under duress (gunpoint) adds humor and intensity to the claim.
The second part transitions into a hypothetical situation involving a pool filled with fruit juice. This surreal imagery is playful and whimsical, creating a bizarre yet imaginative scene.
The text includes practical observations (e.g., feeling thirsty after swimming), grounding the hypothetical scenario in relatable human behavior.
The tone is informal, conversational, and self-aware, with a meandering, stream-of-consciousness quality.
Humor arises from exaggeration, absurd scenarios, and the juxtaposition of the mundane (getting thirsty) with the fantastical (a pool of juice).
While entertaining, the text lacks strict logical coherence. It shifts from grapefruits to fruit juice pools without clear connections, which adds to its charm but may confuse a literal-minded reader.
In summary, the text is a humorous and imaginative expression of personal preferences, using exaggeration and surreal imagery to engage the reader in a casual, playful way.
Hold on, can’t read…lots of fruit juice in the eye. Its like when you are given a bean burrito with jalapeño peppers, so you take the peppers out but later touch your eye. No matter what, don’t touch your eye if you touched peppers.
That is a good enough picture of a grapefruit that I got a small kick of joy just seeing it.
Good job, grapefruit.
Can they make it taste less shitty?
Sprinkle a bit of sugar on there and it’s fantastic. Doesn’t take much, just a touch to offset the bitterness.
Somebody hasn’t tried Fresca
Did. Hated it. Who drinks that crap?
Can we trade situations then? I would like to drink it again.
You don’t have to eat it, you know. And you won’t have any medication problem. It’s a complete win for you.
I don’t eat it. Haven’t eaten it ever after that first time when I bit into it thinking it’s called “grape fruit”.
It IS called grape fruit, not for its taste though, rather for the way the fruits grow in grape-like racemes ;)
Race memes?
Please explain! (And thank you for that explanation)
Those are self-explanatory:
<img alt="" src="https://lemmy.world/pictrs/image/305049d4-022c-4b64-9123-c29551cc86ff.jpeg">